Betamethasone Dipropionate (Topical Application Route) Proper Use - Mayo Clinic.

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- Betamethasone recommended dosage



  However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Child: As betamethasone Na phosphate and betamethasone acetate: Usual dose: 0. Description: Betamethasone is a corticosteroid with primarily glucocorticoid activity. Betamethasone is also available in topical forms, including a cream, gel, lotion, ointment, spray, and foam. Recommended regimens: Short-term treatment: mg daily for the 1st few days, then decrease by 0. Adult: As betamethasone Na phosphate and betamethasone acetate: Usual dose: 0.  


- Betamethasone recommended dosage



  As betamethasone Na phosphate: Usual dose: mg daily in divided doses. Recommended regimens: Short-term treatment: mg daily for the 1st few days, then. Usual Adult Dose for Dermatitis. Cream, gel, ointment: Apply a thin film topically to the affected area 1 or 2 times a day.     ❾-50%}

 

Betamethasone recommended dosage



    Call your doctor right away if you have serious side effects. Drug information provided by: IBM Micromedex. Study Start Date :. Read this next. Patient Counseling Information. Spriggs, M.

Protect from light. Do not freeze. Protect from extreme heat exposure. MIMS Class. ATC Classification. S01BA06 - betamethasone ; Belongs to the class of corticosteroids. Used in the treatment of inflammation of the eye. S02BA07 - betamethasone ; Belongs to the class of corticosteroids used in the treatment of inflammation of the ear.

S03BA03 - betamethasone ; Belongs to the class of corticosteroids used in ophthalmologic and otologic preparations.

R01AD06 - betamethasone ; Belongs to the class of topical corticosteroids used for prophylaxis and treatment of allergic rhinitis. Used in the treatment of dermatological diseases. H02AB01 - betamethasone ; Belongs to the class of glucocorticoids.

Used in systemic corticosteroid preparations. Betamethasone Systemic. Lexicomp Online. Hudson, Ohio. Betamethasone Topical. Source: U. National Library of Medicine. Betamethasone 0. Betamethasone Dipropionate Ointment Prasco Laboratories.

Betamethasone Tablet Y. Industries [M] Sdn Bhd. Betamethasone Valerate 0. Buckingham R ed. Martindale: The Complete Drug Reference [online]. Pharmaceutical Press.

Diprosone 0. Joint Formulary Committee. British National Formulary [online]. Mylan New Zealand Ltd. Beta 0. Vistamethasone 0. Disclaimer: This information is independently developed by MIMS based on Betamethasone from various references and is provided for your reference only.

Therapeutic uses, prescribing information and product availability may vary between countries. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise.

Detailed Description:. Betamethasone is a medicine given to women expected to deliver after 24 but before 34 weeks of pregnancy. It is very advantageous in preventing or decreasing the many problems these small babies may face if born early. Betamethasone makes breathing easier for them, also decreases the chance of them bleeding in the head and makes their chances of survival better.

This medicine is used routinely in pregnancy but the best timing between doses in not well established. The 'standard' dosing schedule involves giving 2 injections of 12mg of the medicine 24 hours apart. However, many women deliver before reaching the hour mark, despite the doctors best efforts to try and delay delivery, and therefore miss the opportunity for the 2nd dose.

FDA Resources. Arms and Interventions. Outcome Measures. Eligibility Criteria. Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Inclusion Criteria: Pregnant women expected to deliver preterm either induced or spontaneously for any obstetrical or medical indication. The amount of medicine that you take depends on the strength of the medicine.

Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. If you miss a dose of this medicine, apply it as soon as possible.

However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. There is a problem with information submitted for this request. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID, plus expertise on managing health. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you.

If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices.

You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. Talk to your doctor to see if this medication is working for you.

You may need to find somewhere to get the injection during your travels. Or your doctor may decide to change your dosing plan. You may need to have lab tests done after you start using betamethasone. Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date.

However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.

The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.

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Study record managers: refer to the Data Element Definitions if submitting registration or results information. Talk with your doctor and family members or friends about deciding to join a study.

To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. We're building a better ClinicalTrials. Check it out and tell us what you think! Hide glossary Glossary Study record managers: refer to the Data Element Definitions if submitting registration or results information.

Search for terms. Save this study. Warning You have reached the maximum number of saved studies Betamethasone Dosing Interval - 12 or 24 Hours? The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. Federal Government. Read our disclaimer for details. Last Update Posted : November 10, Study Description.

The purpose of this study is to determine if there may be a benefit to the newborn if betamethasone is given 12 hours apart instead of 24 hours apart. Detailed Description:. Betamethasone is a medicine given to women expected to deliver after 24 but before 34 weeks of pregnancy.

It is very advantageous in preventing or decreasing the many problems these small babies may face if born early. Betamethasone makes breathing easier for them, also decreases the chance of them bleeding in the head and makes their chances of survival better. This medicine is used routinely in pregnancy but the best timing between doses in not well established. The 'standard' dosing schedule involves giving 2 injections of 12mg of the medicine 24 hours apart. However, many women deliver before reaching the hour mark, despite the doctors best efforts to try and delay delivery, and therefore miss the opportunity for the 2nd dose.

FDA Resources. Arms and Interventions. Outcome Measures. Eligibility Criteria. Information from the National Library of Medicine Choosing to participate in a study is an important personal decision.

Inclusion Criteria: Pregnant women expected to deliver preterm either induced or spontaneously for any obstetrical or medical indication. Gestational age between 23 and 34 weeks gestational age. Dating must either be by LMP which is consistent with ultrasound performed at any gestational age, or calculated by a sonogram less than or equal to 23 weeks. Known drug allergy to betamethasone. Given steroid other than betamethasone for lung maturation.

Any contraindication to steroid therapy. Contacts and Locations. Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.

More Information. A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants. National Library of Medicine U. National Institutes of Health U. Department of Health and Human Services. Preterm Delivery. Drug: dosing of Betamethasone. Not Applicable. Study Type :. Interventional Clinical Trial. Estimated Enrollment :. Study Start Date :. Actual Primary Completion Date :. Actual Study Completion Date :.

March 28, Key Record Dates.

As betamethasone Na phosphate: Usual dose: mg daily in divided doses. Recommended regimens: Short-term treatment: mg daily for the 1st few days, then. Usual Adult Dose for Dermatitis. Cream, gel, ointment: Apply a thin film topically to the affected area 1 or 2 times a day. This medicine is used routinely in pregnancy but the best timing between doses in not well established. The 'standard' dosing schedule. —12 mg (—2 mL)/dose at the appropriate site as follows: very large joint 1—2 mL; large joint 1 mL; medium joint —1 mL; small joint — mL. For. Usual Adult Dose for Dermatological Disorders. Injectable 30 mg/5 mL suspension: Intralesional treatment: mL/cm2 intradermally (do not. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. General disorders and administration site conditions: Malaise. Patient with history of local hypersensitivity to corticosteroids betamethasone valerate ; subjected to stress conditions e.

This information is not country-specific. Please refer to the Malaysia prescribing information. Indications and Dosage. Intra-articular Osteoarthritis, Rheumatoid arthritis Adult: Adjunctive treatment for short term administration: As betamethasone Na phosphate and betamethasone acetate: mg 0. Adult: As betamethasone Na phosphate and betamethasone acetate: Usual dose: 0. Dosage is individualised according to the disease being treated and patient response.

Refer to the disease-specific product guidelines for detailed dosage recommendations. Child: As betamethasone Na phosphate and betamethasone acetate: Usual dose: 0. Adult: For non-infected cases of the nose: As 0.

Use the lowest effective dose for the shortest possible time. Discontinue if there is no clinical response within 7 days of treatment. Child: Same as adult dose. Adult: For short-term treatment of steroid-responsive cases: As 0.

Adult: Dosage is individualised and adjusted according to the disease being treated, its severity and patient response. As betamethasone Na phosphate: Usual dose: 0. Recommended regimens: Short-term treatment: mg daily for the 1st few days, then decrease by 0.

Rheumatoid arthritis: 0. Other conditions: 1. Use the lowest effective dose. Adult: For non-infected cases: As 0. Adult: As betamethasone Na phosphate: mg via slow IV inj over 0.

Use the minimum effective dose. Doses to be given via slow IV inj or infusion, may be repeated times in 24 hours as necessary depending on the condition being treated and patient response. Adult: As 0. Re-evaluate treatment if condition worsens or does not improve within weeks.

Dosage and treatment duration may vary according to the severity of the condition and patient response. Child: As 0. Adult: As betamethasone Na phosphate: mg as local inj into soft tissue lesions; may be repeated on 2 or 3 occasions according to patient response. Untreated systemic infections oral, parenteral ; idiopathic thrombocytopenic purpura IM ; perforated tympanic membrane otic. Ophthalmic: Bacterial, fungal, viral, tuberculous or purulent eye infections; glaucoma, herpetic keratitis e.

Topical: Untreated fungal, tubercular or bacterial skin infections; viral skin lesions e. Concomitant administration with live vaccines in patients receiving immunosuppressive doses. Special Precautions. Patient with history of local hypersensitivity to corticosteroids betamethasone valerate ; subjected to stress conditions e.

Avoid abrupt withdrawal particularly during prolonged therapy. Renal and hepatic impairment. Pregnancy and lactation. Adverse Reactions. Significant: Adrenal suppression e. Rarely, anaphylactoid reactions. Topical: Allergic contact dermatitis, systemic effects e. Blood and lymphatic system disorders: Leucocytosis. Eye disorders: Papilloedema, corneal or scleral thinning, exacerbation of ophthalmic viral or fungal diseases; mydriasis, ptosis, epithelial punctate keratitis ophthalmic.

Gastrointestinal disorders: Abdominal distension, dyspepsia, nausea, oesophageal ulceration, peptic ulcer with perforation and haemorrhage; acute pancreatitis; taste disturbance nasal. General disorders and administration site conditions: Malaise. Investigations: Weight gain. Metabolism and nutrition disorders: Hypokalaemic alkalosis, impaired carbohydrate tolerance. Musculoskeletal and connective tissue disorders: Osteoporosis, tendon rupture, vertebral and long bone fractures, avascular osteonecrosis.

Nervous system disorders: Headache. Psychiatric disorders: Irritability, mania, delusions, hallucinations, behavioural disturbances, anxiety, sleep disturbances, confusion. Reproductive system and breast disorders: Menstrual irregularity, amenorrhoea. Respiratory, thoracic and mediastinal disorders: Nasal irritation and dryness, epistaxis, rebound congestion, bronchial asthma, perforation or ulceration of nasal septum, anosmia, parosmia, sneezing.

Skin and subcutaneous tissue disorders: Atrophy, bruising, acne, telangiectasia, striae, hypertrichosis, Stevens-Johnson syndrome; pruritus, burning or stinging sensation, pain topical.

Vascular disorders: Thromboembolism. Patient Counseling Information. Ophthalmic: This drug may cause visual disturbances such as transient blurred vision; if affected, do not drive or operate machinery. Remove contact lenses prior to instillation of eye drops and wait at least 15 minutes before reinsertion.

Monitoring Parameters. Monitor blood pressure, serum K and glucose, growth in children; signs and symptoms of infection, inj site reactions, HPA axis suppression, adrenal insufficiency. Perform ophthalmic examination periodically. Drug Interactions. May reduce effects of anticholinesterases in patients with myasthenia gravis. Enhanced metabolism and decreased therapeutic effect with rifampicin, carbamazepine, phenobarbitone, phenytoin, primidone, aminoglutethimide, ephedrine.

May antagonise the effects of hypoglycaemic agents e. May enhance the effect of coumarin anticoagulants. Increased renal clearance of salicylates. Increased risk of hypokalaemia with theophylline, carbenoxolone, antifungals e.

May reduce effect with mifepristone. May inhibit the growth promoting effects of somatropin. May increase the risk of tendon rupture with fluoroquinolones. May increase serum concentration with CYP3A4 inhibitors e. Potentially Fatal: May diminish the therapeutic effect of vaccines live or inactivated.

Lab Interference. Description: Betamethasone is a corticosteroid with primarily glucocorticoid activity. It induces phospholipase A 2 inhibitory proteins lipocortins and sequentially inhibits the release of arachidonic acid, thereby depressing the formation, release, and activity of prostaglandins, histamines, and other endogenous inflammatory chemical mediators. Pharmacokinetics: Absorption: Readily absorbed from the gastrointestinal tract oral ; absorbed percutaneously topical.

Time to peak plasma concentration: minutes IV. Distribution: Crosses the placenta and enters breast milk. Metabolism: Metabolised primarily in the liver. Elimination half-life: 6. Chemical Structure. PubChem Database. Protect from light and moisture. Protect from light. Do not freeze. Protect from extreme heat exposure. MIMS Class. ATC Classification. S01BA06 - betamethasone ; Belongs to the class of corticosteroids. Used in the treatment of inflammation of the eye.

S02BA07 - betamethasone ; Belongs to the class of corticosteroids used in the treatment of inflammation of the ear. S03BA03 - betamethasone ; Belongs to the class of corticosteroids used in ophthalmologic and otologic preparations. R01AD06 - betamethasone ; Belongs to the class of topical corticosteroids used for prophylaxis and treatment of allergic rhinitis. Used in the treatment of dermatological diseases. H02AB01 - betamethasone ; Belongs to the class of glucocorticoids.

Used in systemic corticosteroid preparations. Betamethasone Systemic. Lexicomp Online. Hudson, Ohio.



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